Our 2 year old has been on a bunch of flights by now and as I've mentioned in other threads, as long as you're prepared for it you have nothing to worry about.
Sure, it will "detract" from the overall experience when you need to tend to a baby's needs, but the more you do it now the more both you and her will get used to it and eventually enjoy it.
My approach was simple...
you throw the rules out the window. His favorite juice during take-off and landing to keep his ears from bothering him, a tablet with a million hours of Yo Gabba Gabba (and a backup tablet, in case power was an issue) and plenty of NEW toys did the trick. Sure it sucks if both you and your wife can't enjoy meal service at the same time if the baby is up and needs some attention, but that's a small price to pay to be comfortable.
The one piece of invaluable advise I got was to book the flights around nap time. I never thought of it before the first flight because that was never really an issue before, but it helps quite a lot when the baby is used to napping at a certain time and that happens to coincide with shortly after take-off.
I think the first flight or two might be a bit unnerving for an infant but believe me they get used to it in a hurry. And if you do your job right nobody will even know they're in the plane.

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