A friend and I were discussing travel immunizations and our respective takes on them: I've been vaccinated against just about everything, she is willing to take her chances. There are some things I'm just not willing to risk, regardless of the probability. I've met lots of other travelers who take my friend's approach though. A few months ago in Zimbabwe an American couple was telling me that RX malaria pills are worthless and they buy herbal remedies to protect themselves once they arrive. These discussions got me wondering what other FF/frequent travelers do. Do you make sure you're up on everything before each trip? Carry Cipro and other RXs "just in case?" What, if any, herbal or over-the-counter remedies do you recommend? Personally, I take Melatonin on the plane (OTC) and love my emergen-C and multi-vitamins, but I also carry Cipro and any other RXs I may need (Malarone for malarial areas and Metronidazole for areas with giardia). Like I said above, I've been vaccinated for just about everything the CDC recommends for the areas I've been to and I consult my GP if I'm going to a new area. Maybe I'm paranoid!